LDU Quito vs São Paulo Prediction, Betting Tips, Lineups & Odds | 18 Sep 2025

Copa Libertadores Betting Preview: LDU Quito vs São Paulo

Ecuadorian LigaPro team LDU Quito host Brazilian Série A side São Paulo in the first leg of this Copa Libertadores quarter-final tie, with kick-off set for 06:00 on Friday 19 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and confirmed lineups.

We Predict a Close Encounter

The draw can be a favourable outcome when wagering São Paulo +0.5 at an Asian Handicap price of 1.97. Tricolor Paulista should be able to avoid a loss against LDU Quito and this wager has the numbers to secure a return.

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4-2 Victory for LDU in Last H2H

LDU Quito triumphed in their last game. It was on the road at Estadio Federativo Reina del Cisne where Libertad were beaten 1-0 in the LigaPro.

São Paulo claimed a home victory in their previous match. A 1-0 Série A win occurred against Botafogo. Hernan Crespo's men had three shots on goal and 48% possession, with Juan Dinenno striking early in the first half.

In the round of 16, LDU claimed a 2-1 aggregate win over Brazilian Série A club Botafogo, while São Paulo advanced on penalties against Colombian Categoria Primera A side Atlético Nacional after a 1-1 draw on aggregate.

Head-to-Head Statistics

LDU won the last clash between the pair. Landing a 4-2 home victory when facing São Paulo in the Copa Libertadores.

Copa Libertadores		G	W	D	L	GF	GA	GD	GD	P
1	LDU Quito	6	3	2	1	8	4	4	8:4	11
1	São Paulo	6	4	2	0	10	4	6	10:4	14

View Full Table

LDU Quito vs São Paulo Prediction & Betting Tips

Our LDU Quito vs São Paulo betting guide delivers expert insight, including a main match pick, scoreline advice, standout player props and bet builder recommendations. Dive into each section below for more.

Match Prediction

São Paulo look like a great betting option with a +0.5 goal start. They should be able to triumph or potentially draw this Copa Libertadores match, with this Asian Handicap pick at 1.97 looking like value.

The football betting tips stem from knowing the team news and the latest form for each side. We work hard to unearth the most pertinent Copa Libertadores stats which can also act as a guide.

Key LDU Quito vs São Paulo Copa Libertadores & league stats:

• The +0.5 line has been covered by São Paulo in 9 of their last 10 games.
• The +0.5 line has been covered by São Paulo in 4 of their last 5 games.
• The -0.5 line hasn’t been covered by LDU in 6 of their last 10 games.
• The -0.5 line hasn’t been covered by LDU in 3 of their last 5 games.

São Paulo +0.5 Probability

According to the latest odds, there’s a 50.8% likelihood of our pick winning. In our opinion, there’s actually a probability of success between 55-60%. This is why we regard this as a value wager.

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Our Match Prediction

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Correct Score Prediction

LDU 1 - 1 São Paulo

We think there’s a chance of a 1-1 draw and this can be backed at odds of 5.80. We like placing a bet on correct score due to the fun element and the big potential return.

Player Prop Picks

LDU Quito vs São Paulo Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Bookies Have LDU as Favourites

With the bookies giving them a 50% probability of winning, LDU Quito might be a popular acca pick. Their current betting odds are 2.00 when it comes to triumphing in this Copa Libertadores clash. The market implies that São Paulo are the most unlikely to win at 4.70.

Should you want to back LDU to lead at the break, then there is 2.80 available on the Half-Time Result market. Opponents São Paulo have been chalked up at 5.30 and the draw is 1.88.

The Total Goals market is a great option and Under 2.5 Goals has the shortest odds right now. A fresh approach might involve siding with a BTTS wager and there’s 1.47 on offer for Both Teams to Score No.

Hundreds of markets are now a guarantee for each of the Copa Libertadores games, with the best football betting sites making sure that customers have quality options.

Michael Estrada Top of First Goalscorer List

There’s the chance to back Michael Estrada at 7.00 to be the First Goalscorer. He’s the favourite and available at similar odds to find the net last instead.

Latest Copa Libertadores and domestic league stats. Full Time Result, Goals, Corners and Possession.

LDU Quito Stats

São Paulo Stats

Full-Time Result

• 5 wins, 2 defeats and 3 draws in the previous 10 matches
• 4 wins and 6 draws in the previous 10 home matches

Full-Time Result

• 7 wins, 1 defeat and 2 draws in the previous 10 matches
• 2 wins, 4 defeats and 4 draws in the previous 10 away matches

Goals

• An average of 1.40 goals scored and 0.70 conceded in the previous 10 matches
• An average of 1.80 goals scored and 1.20 conceded in the previous 10 home matches
• An average of 2.10 goals per game in the previous 10 matches
• An average of 3.00 goals per game in the previous 10 home matches
• BTTS Yes in 4 of the previous 10 matches
• BTTS Yes in 9 of the previous 10 home matches
• Over 2.5 Goals in 3 of the previous 10 matches
• Over 2.5 Goals in 5 of the previous 10 home matches

Goals

• An average of 1.70 goals scored and 0.70 conceded in the previous 10 matches
• An average of 1.10 goals scored and 1.40 conceded in the previous 10 away matches
• An average of 2.40 goals per game in the previous 10 matches
• An average of 2.50 goals per game in the previous 10 away matches
• BTTS Yes in 4 of the previous 10 matches
• BTTS Yes in 6 of the previous 10 away matches
• Over 2.5 Goals in 4 of the previous 10 matches
• Over 2.5 Goals in 5 of the previous 10 away matches

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LDU Quito vs São Paulo Lineups & Team News

Be prepared — check the LDU vs São Paulo team news before wagering. We’ll offer the predicted and confirmed Copa Libertadores lineups along with the latest injury developments.