Reading vs Leyton Orient Prediction, Betting Tips, Lineups & Odds | 20 Sep 2025

League One Betting Preview: Reading vs Leyton Orient

Reading host Leyton Orient in this League One encounter at Select Car Leasing Stadium, with kick-off set for 22:00 on Saturday 20 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and confirmed lineups.

O's to Put Up a Fight Against Royals

The best plan could involve backing Leyton Orient with a +0.25 Asian Handicap at 1.64 when clashing with Reading. Our stake is split between 0 and +0.5, allowing us to land a return in the event of a draw.

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Orient Won When They Last Played Reading

Reading suffered a defeat in their last game. A 3-2 scoreline occurred away from home at Oakwell Stadium against Barnsley.

Leyton Orient played Bolton Wanderers at home in their previous game. It was a 1-1 draw at BetWright Stadium.

Head-to-Head Statistics

Orient have won the last two encounters against Reading. A 2-0 home win at Gaughan Group Stadium came after a 1-0 victory away at Select Car Leasing Stadium. The previous 4 H2H games have featured three Orient victories and one draw.

League One		G	W	D	L	GF	GA	GD	GD	P
14	Leyton Orient	8	3	2	3	10	13	-3	10:13	11
21	Reading	7	1	2	4	7	12	-5	7:12	5

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Reading vs Leyton Orient Prediction & Betting Tips

Our Reading vs Leyton Orient betting preview covers everything you need, including a key match prediction, correct score insight, top player prop bets and a value-packed bet builder recommendation.

Match Prediction

We’ll side with Leyton Orient +0.25 for this League One clash, with an attractive 1.64 available. Our verdict is that they’ll perform strongly and the Asian Handicap line looks generous for this outcome.

Understanding the injured players situation proves useful when assembling football picks. Once we’ve also considered the form guide, we use the latest stats and provide League One betting predictions.

Key Reading vs Leyton Orient league stats:

• The +0.25 line has been covered by Orient in 15 of their last 20 games.
• The +0.25 line has been covered by Orient in 7 of their last 10 games on the road.
• The +0.25 line has been covered by Orient in 2 consecutive games.
• The -0.25 line hasn’t been covered by Reading in 4 of their last 5 games.
• The -0.25 line hasn’t been covered by Reading in 7 of their last 10 games.
• The -0.25 line hasn’t been covered by Reading in 4 consecutive games against Orient.

Orient +0.25 Probability

According to the top bookies, our pick has a 61% chance of landing a return. However, our tipsters have this number closer to 70% based on their in-depth research. That means we’re regarding it as a value bet.

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Our Match Prediction

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Correct Score Prediction

Reading 1 - 2 Leyton Orient

Leyton Orient are available at 7.50 to secure a 2-1 victory. Many bettors enjoy a correct score wager and there are some nice potential returns to be had.

Player Prop Picks

Reading vs Leyton Orient Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Close Game On the Cards According to Latest Odds

The draw is currently trading at 3.50 if you think this League One encounter will end all square, while Reading have betting odds of 2.48 and Leyton Orient are 2.55 to land a victory of their own.

As the name suggests, the Draw No Bet market means money back if the game ends level. Should you take this option, then you can choose between Reading at 1.81 and Orient at 1.85.

You can land odds which are similar whether you’re backing Over or Under 2.5 Goals. The Yes option in the Both Teams to Score market is regarded as the most likely outcome and is trading at 1.68.

The leading football betting sites provide bettors with an abundance of options. For every League One match, you’re able to select from hundreds of markets and make the best choice.

Jack Marriott Favourite to Find the Net First

Those interested in favourite Jack Marriott to find the net first can get 5.50, while the Anytime Goalscorer angle could hold more appeal and this is 3.05.

Reading Have Five Wins From Previous Ten Home Games

Reading have finished with five wins, four losses and one draw in the last 10 home matches, scoring an average of 1.30 goals per game and conceding 1.20.

Orient have collected six victories, three losses and one draw in the last 10 away games, recording an average of 1.80 goals per match and conceding 1.60.

Orient beat Reading 1-0 when they last met at Select Car Leasing Stadium.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Reading Home Stats		5-1-4	2.50	1.30	1.20	4	6	5	5
Leyton Orient Away Stats		6-1-3	3.40	1.80	1.60	7	3	7	3

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

Reading vs Leyton Orient Lineups & Team News

Don’t bet on Reading vs Orient without reviewing the latest team news. Get the latest predicted and confirmed League One lineups and injury news right here.

Reading Team Page Leyton Orient Team Page