San Luis vs América Prediction, Betting Tips, Lineups & Odds | 24 Sep 2025

Liga MX Betting Preview: San Luis vs América

San Luis host América in this Liga MX encounter at Estadio Alfonso Lastras, with kick-off set for 11:00 on Thursday 25 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

We’re Keen on BTTS Yes

Let’s take a chance on the BTTS Yes option when it comes to San Luis and América clashing. We really like the 1.64 that is available and feel confident that the teams can both find the net.

Confident in this BTTS pick? Unlock the new Stake promo code and check out our in-depth expert review before making your move.

7 Wins for América in Last 10 H2H Encounters

Atlético San Luis triumphed in their last game which was away from home. Santos Laguna were beaten 4-1 at Estadio Nuevo Corona. Los Atléticos recorded eight shots on target and had 47% possession, with Joao Pedro scoring two, while Juan Sanabria and Benjamin Galdames also getting a goal.

Club América played out a 2-2 draw in their previous game. This was on their travels to Estadio BBVA, with Monterrey the opponents. Andre Jardine's men had 49% of possession and eight shots on goal, while Rodrigo Aguirre and Ramon Juarez found the net.

Head-to-Head Statistics

América beat San Luis at home when the teams last met. It was a 3-0 scoreline at Estadio Azteca. The previous 10 H2H meetings have seen América land seven wins and San Luis winning the other matches.

Liga MX		G	W	D	L	GF	GA	GD	GD	P
4	América	9	5	3	1	18	10	8	18:10	18
11	San Luis	9	3	1	5	15	15	0	15:15	10

View Full Table

San Luis have 4 wins, 5 losses and 1 draw, averaging 1.7 goals from 4.5 shots on goal and 7.5 attempts. Guillermo Abascal's team have averaged 48.1% possession and 4.3 corners per game, with their opponents scoring 1.6 goals from 5.4 shots on goal, 9.9 attempts and 5.6 corners.

Top scorer is Joao Pedro on 8 goals, while Benjamin Galdames has racked up 3 and Roman Torres 2. Sebastien Lamonge is the top assists maker on 2.

Club América have won 5, lost 2 and drawn 3, with an average of 9.3 attempts, 4.4 shots on goal and 1.8 goals. Las Águilas average 59.0% possession, 6.4 corners awarded and 3.7 corners against them, while 1.2 goals have been conceded from 3.1 shots on goal and 6.6 attempts.

Brian Rodriguez is top of the team’s scoring charts with 3, while Rodrigo Aguirre, Alex Zendejas, Allan Saint-Maximin and Erick Sanchez have 2. Brian Rodriguez has been top assists provider with 3 in the previous 10 games.

Predicted & Confirmed Lineups

San Luis predicted lineup (4-2-3-1): Andrés Sánchez (GK), Román Torres, Eduardo Águila, Robson Bambu, Juan Manuel Sanabria, Óscar Macías, Sébastien Salles Lamonge, Miguel García, Sebastián Pérez Bouquet, Benjamín Galdames, João Pedro Galvão.

América predicted lineup (4-2-3-1): Luis Malagón (GK), Dagoberto Espinoza, Sebastián Cáceres, Ramón Juárez, Cristian Borja, Israel Reyes Romero, Alan Cervantes, Alejandro Zendejas, Alexis Gutiérrez, Allan Saint-Maximin, José Zúñiga.

San Luis vs América Prediction & Betting Tips

Head into San Luis vs América with expert betting insights, including our main match prediction, expected scoreline, top corners angle, key player props and a thoughtfully built bet builder.

Match Prediction

There’s an opportunity to bet on BTTS Yes when it comes to this Liga MX clash. The odds of 1.64 are really attractive and we anticipate that the teams will be among the goals.

Plenty of research goes into our football picks. It begins by focusing on the latest Liga MX form and knowing the injury situation. The important numbers can then be utilised to help complete the picture.

Key San Luis vs América league stats:

• BTTS Yes has been covered in 4 straight San Luis games.
• BTTS Yes has been covered in 7 of the last 10 San Luis games.
• BTTS Yes has been covered in 14 of the last 20 San Luis games.
• BTTS Yes has been covered in 5 straight América games on the road.
• BTTS Yes has been covered in 7 of the last 10 América games.
• BTTS Yes has been covered in 11 of the last 20 América games on the road.

BTTS Yes Probability

The latest betting odds imply that our pick has a 61% prospect of winning. However, our tipsters have this number closer to 70% based on their in-depth research. This is why we can recommend this wager.

An alternative to BTTS Yes is going for Over 2.5 Goals to be scored. With this bet, it doesn’t matter which team scores providing that there are at least three goals in total.

Don’t place another bet without seeing the best betting offers available—free bets and welcome promos included.

Our Match Prediction

Stake Promo 200% up to $2000 + 5% Rakeback T&C apply. Gamble responsibly 18+

Gamble responsibly 18+. All odds are correct at time of publishing and are subject to change. To use the Bookmaker Live Streaming services you will need to be logged in and have a funded account or to have placed a bet in the last 24 hours. Geo-restrictions apply.

Correct Score Prediction

San Luis 1 - 2 América

We’ve found an attractive bet at odds of 7.50 and it involves América winning 2-1. We like a wager on correct score as there’s the chance to bank a bigger return.

Player Prop Picks

Corners Prediction

San Luis Under 4.5 Corners

San Luis have failed to cover the 4.5 corners line in three consecutive matches, with América conceding under 4.5 corners in their past four games. We think San Luis might fall short of the mark, with odds of 1.73 available when it comes to this Team Corners pick.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

San Luis

Total

9.90 4.30 5.60

Home

9.40 4.50 4.90

Away

12.00 5.50 6.50

América

Total

10.10 6.40 3.70

Home

9.70 6.30 3.40

Away

8.90 4.60 4.30

Latest Corner Odds

Total Corners

San Luis Corners

América Corners

Most Corners

T&C apply. Gamble responsibly 18+

San Luis vs América Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

América Made Favourites by the Bookies

The latest Club América odds are 1.68 which leads to them being favourites in this Liga MX clash. It’s also implied by the bookmakers that they have a 60% prospect of securing a victory. At 4.30, Atlético San Luis are regarded as having a lower probability of winning.

América -0.75 on the Asian Handicap is available at 1.90 and means a full payout if they win by two or more against San Luis. A victory by one goal means half the stake wins and the other half is refunded.

The odds suggest that Over 2.5 Goals is a strong probability in this exciting contest. For those expecting both sides to find the net, Both Teams to Score Yes is available at 1.64.

The best football betting sites cover Liga MX games in serious depth and there are hundreds of markets. We recommend scanning through the various bets before picking out the best angle.

Rodrigo Aguirre Favourite to Be First Goalscorer

Rodrigo Aguirre can be backed to find the net anytime at 2.65, with 5.50 available that the market leader scores the first goal.

Seven América Wins in Past Eight H2H Estadio Alfonso Lastras Clashes Against San Luis

San Luis haven’t triumphed in four straight games at Estadio Alfonso Lastras. Los Atléticos have five defeats, four victories and one draw in the last 10 home matches, netting an average of 1.20 goals per game and conceding 1.30.

América are unbeaten over their previous five games on the road. Andre Jardine's side have four draws, four losses and two victories in the last 10 away matches, recording an average of 1.10 goals per game and conceding 1.20.

The last Estadio Alfonso Lastras meeting saw San Luis beat América 2-1. América have won seven of the past 8 H2H games at Estadio Alfonso Lastras, with San Luis picking up one win.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
San Luis Home Stats		4-1-5	2.50	1.20	1.30	6	4	7	3
América Away Stats		2-4-4	2.30	1.10	1.20	3	7	5	5

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

You can watch and bet on Liga MX games thanks to the live streaming service that’s available. This is only available to eligible sportsbook customers and is subject to geo-restrictions.

Fans love the opportunity to watch thousands of sporting events per year with the best betting apps.

San Luis vs América Live Streaming  Watch Live Geo-restrictions apply. To use the services you need to be logged in, a funded account or to have placed a bet in the last 24 hours.

San Luis vs América Lineups & Team News

Stay ahead of the game by checking the San Luis vs América team news before betting. We’ll share both predicted and confirmed lineups for the Liga MX along with the latest injury news.

San Luis Team Page América Team Page