Sassuolo vs Lazio Prediction, Betting Tips, Lineups & Odds | 14 Sep 2025

Serie A Betting Preview: Sassuolo vs Lazio

Sassuolo host Lazio in this Italian Serie A encounter at Stadio Mapei, with kick-off set for 00:00 on Monday 15 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

We’re Backing Lazio to Win

We’re keen to secure odds of 2.02 for an away win when Lazio face Sassuolo. There’s every chance that the visitors will have the edge and the Full-Time Result market offers plenty of value.

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Last H2H Encounter Ended in a 1-1 Draw

Sassuolo have lost back-to-back Serie A games. Away at Stadio Giovanni Zini, Cremonese recently beat them 3-2. Fabio Grosso's team enjoyed 58% possession and had five shots on target, with Andrea Pinamonti and Domenico Berardi scoring one goal apiece.

Lazio claimed a home victory in their previous game. A 4-0 win occurred against Hellas Verona at Stadio Olimpico. Le Aquile racked up six shots on goal and boasted 70% possession, while Matteo Guendouzi, Mattia Zaccagni, Valentin Castellanos and Boulaye Dia were on the scoresheet.

Head-to-Head Statistics

Lazio haven’t lost to Sassuolo in their past five games, with the last clash ending 1-1 at Stadio Olimpico. The 10 previous H2H meetings have involved six Lazio wins, one draw and three Sassuolo victories.

Serie A		G	W	D	L	GF	GA	GD	GD	P
12	Lazio	3	1	0	2	4	3	1	4:3	3
14	Sassuolo	3	1	0	2	3	5	-2	3:5	3

View Full Table

Sassuolo have 4 wins, 5 losses and 1 draw, averaging 1.8 goals from 5.0 shots on goal and 9.7 attempts. The Emilia-Romagna club have averaged 49.5% possession and 4.1 corners per game, with their opponents scoring 1.6 goals from 5.2 shots on goal, 10.6 attempts and 5.0 corners.

Top goalscorer Armand Lauriente has found the net 5 times, with Domenico Berardi, Simone Verdi, Daniel Boloca and Luca Moro scoring 2 each. Cristian Volpato is the top assists maker on 3.

Lazio have 4 victories, 2 defeats and 4 draws, averaging 4.9 shots on goal, 13.3 attempts and 1.4 goals. Le Aquile average 56.4% possession, 476.6 passes, 6.0 corners taken and 4.4 corners against them, while 0.9 goals have been conceded from 9.8 attempts and 3.6 shots on goal.

Pedro Rodriguez has scored 4, followed by Boulaye Dia on 3 and Valentin Castellanos with 2. Luca Pellegrini is top assists provider with 3, while Christos Mandas and Ivan Provedel have kept 3 clean sheets between them in the last 10 games.

Confirmed Lineups

Sassuolo confirmed lineup (4-3-3): Arijanet Muric (GK), Sebastian Walukiewicz, Jay Idzes, Tarik Muharemovic, Josh Doig, Aster Vranckx, Nemanja Matic, Ismael Kone, Domenico Berardi, Andrea Pinamonti, Armand Lauriente.

Lazio confirmed lineup (4-3-3): Ivan Provedel (GK), Adam Marusic, Mario Gila, Alessio Romagnoli, Nuno Tavares, Matteo Guendouzi, Nicolo Rovella, Fisayo Dele-Bashiru, Matteo Cancellieri, Valentin Castellanos, Mattia Zaccagni.

Sassuolo vs Lazio Prediction & Betting Tips

Take in the full Sassuolo vs Lazio betting outlook — from our expert match prediction and correct score pick to sharp corners advice, player prop insights and a bet builder tailored for value.

Match Prediction

We think Lazio stand a strong chance of victory when they compete in this Serie A game, with our pick providing lots of value. Secure the odds of 2.02 that the visitors are able to get the job done.

We take note of any injuries or suspensions affecting each side before going ahead with our football predictions. The Serie A form guide and stats also help the team at jeetwin24.com crunch the numbers ahead of the action.

Key Sassuolo vs Lazio league stats:

• Lazio have won 6 of their last 10 games on the road.
• Lazio have won 3 of their last 5 games on the road.
• Sassuolo have lost 6 of their last 10 games against Lazio.

Lazio to Win Probability

If you go by the top bookies, there’s a 49.5% likelihood of our pick winning. However, our research has found that the actual probability is between 55-60%. It’s why we think it’s worth placing this bet.

If you think the price for Lazio to win is too short, then consider boosting your odds by pairing this selection with both teams to score on the Result & BTTS market.

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Our Match Prediction

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Correct Score Prediction

Sassuolo 0 - 1 Lazio

An exciting bet could be a 1-0 victory in favor of Lazio at odds of 8.00. A correct score wager provides a fun alternative and a nice potential return on the cards.

Player Prop Picks

Corners Prediction

Lazio Under 5.5 Corners

It’s been an average of 4.00 corners for Lazio in their past 5 away games, with Sassuolo conceding under 5.5 corners in the previous six matches. It stands to reason that the line won’t be reached and you can secure odds of 1.73 for this Lazio Team Corners bet.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Sassuolo

Total

9.10 4.10 5.00

Home

8.70 4.80 3.90

Away

8.60 3.30 5.30

Lazio

Total

10.40 6.00 4.40

Home

10.80 7.80 3.00

Away

10.30 4.50 5.80

Latest Corner Odds

Total Corners

Sassuolo Corners

Lazio Corners

Most Corners

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Sassuolo vs Lazio Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Lazio Have the Shortest Odds to Win

With the bookies giving them a 50% probability of winning, Lazio might be a popular acca pick. Their current betting odds are 2.00 when it comes to triumphing in this Serie A clash. Sassuolo are operating at larger odds than the opposition and the underdogs can be wagered at 3.65.

Lazio are 2.00 on the Asian Handicap -0.5 which is like backing them on the Full-Time Result market. Alternatively, you can get 1.80 for Sassuolo +0.5 and get the draw on your side.

If you want to bet on the number of goals, you can get a similar price on Over or Under 2.5 Goals. BTTS betting is always a warm order and you can bet Yes at 1.70 on the Both Teams to Score market.

It’s fantastic to find hundreds of markets on offer for Serie A matches. You simply need to visit the best betting apps and select from the various football options that are presented.

Valentín Castellanos Top of First Goalscorer List

Favourite Valentín Castellanos is priced at 5.75 to be the first player to find the net. There’s also the opportunity to back him to score any time at odds of 2.95.

Sassuolo Home Form Not Convincing

The previous three Sassuolo matches at Stadio Mapei have seen them beaten. I Neroverdi have managed six victories, three losses and one draw in the last 10 home matches, recording an average of 1.80 goals per game and conceding 1.00.

Lazio have recorded six victories, two draws and two defeats in the previous 10 away matches, netting an average of 1.30 goals per game and conceding 1.10.

Lazio enjoyed a 2-0 winning scoreline when last meeting Sassuolo at Stadio Mapei. The previous 5 H2H meetings at Stadio Mapei have involved Lazio winning three times and Sassuolo registering two victories.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Sassuolo Home Stats		6-1-3	2.80	1.80	1.00	2	8	3	7
Lazio Away Stats		6-2-2	2.40	1.30	1.10	5	5	3	7

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

Sassuolo vs Lazio Lineups & Team News

Always review the Sassuolo vs Lazio team news before locking in your bets. We’ll share both predicted and confirmed lineups for Serie A along with the latest injury news.

Sassuolo Team Page Lazio Team Page